MicroRNAs in Cancer.

By R. Garzon, George A. Calin, Carlo Maria Croce. Annual Review of Medicine, 2009

3,935 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b72911396cc2bda50de1510e4b77ee80c8614dfd

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Citations in the corpus

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). (2009, background): “The most extensively studied among them are microRNAs (miRNAs) that regulate target mRNA post-transcriptionally in animals and plants (for review, see Bartel 2004; Du and Zamore 2005; Lee and Dutta 2009).”
Common features of microRNA target prediction tools (2014, background): “…in 1993 (Lee et al., 1993; Wightman et al., 1993), miRNAs have been identiﬁed as key regulators of proliferation, differentiation, and cell death in both normal and aberrant pathways (Friedman and Jones, 2009; Garzon et al., 2009; Ambros, 2011; Starega-Roslan et al., 2011; Iuliano et al., 2013).”
Posttranscriptional regulation of microRNA biogenesis in animals. (2010, background): “…the most abundant classes of gene-regulatory molecules in animals. miRNAs are involved in a broad range of developmental and physiological processes (Bushati and Cohen 2007); thus, their deregulation is closely linked to human diseases, such as cancer (Chang and Mendell, 2007; Garzon et al., 2009).”
mirDIP 4.1—integrative database of human microRNA target predictions (2017, methodology): “To do this, we used F-score as a measure of prediction performance, calculated across h top-ranked predictions from the given resource, where h was increasing exponentially from 10 3 to 10 6 .”
MicroRNA (miRNA) in cancer (2015, background): “Introduction MicroRNAs (miRNAs) are small non-coding regions in RNAs of 20–22 nucleotides, which play an important role in all biological pathways in multicellular organisms including mammals [1].”
Circulating microRNAs, potential biomarkers for drug-induced liver injury (2009, background): “Even though the biological function of miRNA is yet to be fully understood, it has been shown that the tissue levels of specific miRNAs correlate well with the pathological development of several different cancers (20, 21).”
Non‐coding RNAs: regulators of disease (2010, background): “Indeed, altered expression of a broad suite of miRNAs that, dependent on their targets can either act as tumour suppressors or oncogenes (so-called oncomiRs), has been detected in virtually all cancer types examined (for reviews and tables of cancer-associated miRNAs and their targets, see [134,151,”