ABFs, a Family of ABA-responsive Element Binding Factors*

By Hyung-in Choi, Jung-Hee Hong, J. Ha, J. Kang, S. Kim. Journal of Biological Chemistry, 2000

1,215 citations recorded by the source corpus.

Abscisic acid (ABA) plays an important role in environmental stress responses of higher plants during vegetative growth. One of the ABA-mediated responses is the induced expression of a large number of genes, which is mediated bycis-regulatory elements known as abscisic acid-responsive elements (ABREs). Although a number of ABRE binding transcription factors have been known, they are not specifically from vegetative tissues under induced conditions. Considering the tissue specificity of ABA signaling pathways, factors mediating ABA-dependent stress responses during vegetative growth phase may thus have been unidentified so far. Here, we report a family of ABRE binding factors isolated from young Arabidopsis plants under stress conditions. The factors, isolated by a yeast one-hybrid system using a prototypical ABRE and named as ABFs (ABREbinding factors) belong to a distinct subfamily of bZIP proteins. Binding site selection assay performed with one ABF showed that its preferred binding site is the strong ABRE, CACGTGGC. ABFs can transactivate an ABRE-containing reporter gene in yeast. Expression of ABFs is induced by ABA and various stress treatments, whereas their induction patterns are different from one another. Thus, a new family of ABRE binding factors indeed exists that have the potential to activate a large number of ABA/stress-responsive genes inArabidopsis.

Subfields: Plant Science

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Citations in the corpus

Molecular networks regulating Arabidopsis seed maturation, after-ripening, dormancy and germination. (2008, background): “A typical ABRE contains an ACGT nucleotide core motif recognized by bZIP transcription factors (Hobo et al., 1999; Choi et al., 2000; Finkelstein & Lynch, 2000; Uno et al., 2000).”
Transcription factors in plants and ABA dependent and independent abiotic stress signalling (2010, background): “A coupling element (CE3) is needed to specify the function of ABRE for the expression of ABA ABF1 cold ABF2 salt ABF3 salt ABF4 yes drought Choi et al. 2000 GmbZIP44 yes drought, salt, water stress GmbZIP62 yes cold, drought, salt GmbZIP78 yes drought, salt Liao et al. 2008a GmbZIP132 yes cold,…”
The role of ABA and MAPK signaling pathways in plant abiotic stress responses. (2014, methodology): “ABRE-binding factors (ABFs), were first isolated using ABRE sequences as bait in yeast one hybrid screens (Choi et al., 2000; Uno et al., 2000).”
General mechanisms of drought response and their application in drought resistance improvement in plants (2014, background): “Drought stress induces the biosynthesis of intracellular ABA which activates the corresponding transcription factors, and then promotes the expression of downstream drought-related genes [140].”
Characterization of OsbZIP23 as a Key Player of the Basic Leucine Zipper Transcription Factor Family for Conferring Abscisic Acid Sensitivity and Salinity and Drought Tolerance in Rice1[W][OA] (2008, background): “Previously reported members of the third subfamily in Arabidopsis were designated ABA-responsive element (ABRE)-binding factors, abbreviated as ABFs (i.e. ABF1–ABF4) or AREBs (i.e. AREB1–AREB3; Choi et al., 2000; Uno et al., 2000; Kim et al., 2004).”
A dehydration-induced NAC protein, RD26, is involved in a novel ABA-dependent stress-signaling pathway. (2004, background): “tion factors containing a basic leucine zipper structure (Choi et al., 2000; Finkelstein and Lynch, 2000; Hobo et al., 1999; Uno et al., 2000).”
Three Arabidopsis SnRK2 protein kinases, SRK2D/SnRK2.2, SRK2E/SnRK2.6/OST1 and SRK2I/SnRK2.3, involved in ABA signaling are essential for the control of seed development and dormancy. (2009, background): “Choi et al. (2000) also isolated ABF1, ABF2 (= AREB1), ABF3 and ABF4 (= AREB2) as ABRE-binding factors.”
Abscisic Acid Signaling in Seeds and Seedlings Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010441. (2002, background): “Only one bZIP subfamily has been linked genetically to ABA response: that composed of ABI5 and its homologs, the ABRE binding factors (ABFs and AREBs) (Choi et al., 2000; Uno et al., 2000), and AtDPBFs ( Arabidopsis thaliana Dc3 promoter binding factors) (T. Thomas, personal communication).”
Role of Plant Transcription Factors in Abiotic Stress Tolerance (2011, background): “AREB/ABF genes are mostly redundant in tissue-specific expression either in vegetative tissues or seeds (Choi et al., 2000; Uno et al., 2000).”
Drought and Salt Tolerance in Plants (2005, background): “ABRE binding factors (ABFs)/ABA-responsive element binding (AREBs) proteins respond at the transcriptional and post-transcriptional level to dehydration and salt stress (Choi et al., 2000; Uno et al., 2000).”
Markers associated with a QTL for grain yield in wheat under drought (2007, background): “1995) and dehydrin (Dhn6) (Choi et al. 2000) have been reported on this chromosome in barley.”
Transcriptional regulatory networks in cellular responses and tolerance to dehydration and cold stresses. (2006, methodology): “Arabidopsis cDNAs encoding the bZIP transcription factors referred to as ABREbinding (AREB) proteins or ABRE-binding factors (ABFs) were isolated using the yeast one-hybrid screening method (16, 117).”