The human CENP-A centromeric nucleosome-associated complex

761 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres. (2009, neutral): “…interacting with CENP-A on chromatin (Foltz et al., 2006; Izuta et al., 2006; Obuse et al., 2004), including a six-com-ponent CENP-A nucleosome-associated complex (CENP-A NAC ) that acts as a foundation for assembly of the CENP-A-nucleo-some distal complex (CENP-A CAD ) (Foltz et al., 2006).”
Propagation of centromeric chromatin requires exit from mitosis (2007, background): “We have previously reported that transgeneencoded CENP-A expression leads to reduction of the endogenous CENP-A pool through competition at the protein level (Foltz et al., 2006).”
The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics (2010, positive): “…the most complex cellular substructures (Cheeseman and Desai, 2008), with over 120 constituents described by a range of approaches (Earnshaw and Rothﬁeld, 1985), including targeted proteomic studies (Obuse et al., 2004; Foltz et al., 2006; Okada et al., 2006; Hori et al., 2008; Amano et al., 2009).”
Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP. (2009, neutral): “Both were also previously found to be associated with CENP-A nucleosomes present within centromeric chromatin, albeit at substantially lower levels as judged by silver staining and mass spectrometry (Foltz et al., 2006).”