Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

By M. Pirmohamed, Sally James, S. Meakin, C. Green, A. K. Scott, Thomas J Walley, K. Farrar, Kevin Park, A. Breckenridge, J. Guise and 5 more. British medical journal, 2004

3,313 citations recorded by the source corpus.

Subfields: Geriatrics and Gerontology, Pharmacology, Toxicology

View Paper: https://www.semanticscholar.org/paper/b6bf558edda0378cd756a0267801164109f5f5c5

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Citations in the corpus

Frequency of and Risk Factors for Preventable Medication-Related Hospital Admissions in the Netherlands (2009, background): “6) Oral antidiabetics (4), laxatives (4), diuretics (4), opiates (3), loperamide (3), statins (3), antibacterial drugs (3) Circulatory system: cardiovascular symptoms (eg, dysrhythmias, heart failure) 35 (10.”
The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification. (2013, background): “It has been estimated that DDIs account for up to 4% of ospital admissions in western countries (Bjorkman et al., 2002; irmohamed et al., 2004; Qato et al., 2008), and this may increase nto the future as a result of an ageing population with multiple coorbidities and the inevitable trend towards pol”
Linking Biochemical Pathways and Networks to Adverse Drug Reactions (2014, background): “hospital admissions, which costs the National Health Service (NHS) up to £466 million annually [4].”
Pharmacovigilance from social media: mining adverse drug reaction mentions using sequence labeling with word embedding cluster features (2015, background): “INTRODUCTION Adverse drug reactions (ADRs) are a major public health concern and are among the top causes of morbidity and mortality.(1)”
Gender in cardiovascular diseases: impact on clinical manifestations, management, and outcomes. (2016, background): “Sixty percentage of all patients admitted to the hospital for adverse drug events are women.(150) – 154 Predominantly women display dose-related adverse drug events(154) that may be due to the fact”
The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995–2010 (2015, background): “5% of all emergency hospital admissions are attributable to adverse drug events (ADEs), and at least half of these are judged preventable [1,2].”
Identification of Adverse Drug Events from Free Text Electronic Patient Records and Information in a Large Mental Health Case Register (2015, methodology): “A 2004 analysis of 18,820 patients showed that the projected annual costs for ADRs that led to hospital admissions would total 5466m [3].”
Adverse Drug Reactions in Hospital In-Patients: A Prospective Analysis of 3695 Patient-Episodes (2009, background): “. In a study of almost 19000 admissions, we were able to show that 6.5% of patient admissions to two National Health Service (NHS) hospitals in the UK were related to an ADR”
Using Reinforcement Learning to Personalize Dosing Strategies in a Simulated Cancer Trial with High Dimensional Data (2017, background): “Adverse reactions to drugs alone contribute to significant public health burden despite these drugs being shown to be beneficial (on average) in clinical trials (Pirmohamed et al. 2004).”