Named Series: Twenty Years of Brain, Behavior, and Immunity Twenty years of research on cytokine-induced sickness behavior

By Robert Dantzer, Keith W. Kelley. 2007

1,369 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/b633dadbd0bb4bf9471abecb8b3c73bc405a0d4c

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Citations in the corpus

Positive Emotions Broaden and Build (2012, background): “…of depression, which asserts that basal production levels of inflammatory mediators in peripheral tissues signal the brain to produce “sickness behaviors” including decreased positive affect andmotivation and increased negative affect and social withdrawal (Dantzer, 2001; Dantzer & Kelley, 2007).”
Low-grade inflammation, diet composition and health: current research evidence and its translation (2015, unknown): “CNS responses to (patho)physiological stimuli, such as genuine infections or low-grade inﬂammation as a result of the MetS, are less well described.”
PREVALENCE, MECHANISMS, AND MANAGEMENT OF CANCER-RELATED COGNITIVE IMPAIRMENT (2014, background): “…’ (e.g. fatigue, sleep dysfunction, loss of appetite, withdrawal and other psychological symptoms: all symptoms experienced by cancer patients) (Dantzer & Kelley, 2007), and this has led several investigators to propose infl ammation as central to CRCI aetiology (Ahles & Saykin, 2007;…”
From Stress to Inflammation and Major Depressive Disorder: A Social Signal Transduction Theory of Depression (2014, background): “In the late 1980s, scientists articulated that sickness behaviors represent an organized, highly adaptive response to infection (Hart, 1988) and that this response is mediated by cytokines (Dantzer & Kelley, 1989, 2007).”
Inflammatory Cytokines in Depression: Neurobiological Mechanisms and Therapeutic Implications (2013, background): “…administration of cytokines or activation of the innate immune system can induce a behavioral repertoire termed “sickness behavior” that includes anhedonia, anorexia, fever, sleep changes, and decreased social interaction (Dunn and Swiergiel, 1998, Dunn et al., 2005, Dantzer and Kelley, 2007).”
The behavioral immune system: Current concerns and future directions (2018, background): “…substantial costs, people and other animals have evolved a broad range of responses intended to cope with pathogens, including cultural adaptations such as food handling practices (Billing & Sherman, 1998; Henrich, 2015) and biological adaptations such as sickness behavior (Dantzer & Kelley, 2007).”
From inflammation to sickness and depression: when the immune system subjugates the brain (2008, background): “They are viewed as uncomfortable but banal components of infection”
Depression as a microglial disease. (2015, background): “In view of the substantial correlation between peripheral and central inflammatory states [169], the levels of peripheral inflammatory markers can serve as surrogate markers for microglial status.”
Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System (2009, background): “Numerous studies have now demonstrated that these behaviors are organized, adaptive strategies that are critical to host survival (Dantzer and Kelley, 2007; Nesse and Williams, 1994).”
Curcumin and cancer: an "old-age" disease with an "age-old" solution. (2008, background): “Animal models of ‘‘sickness behavior” support this thesis [236,237], in that fluctuations in inflammatory cytokines, primarily IL-1, IL-6, and TNF-a, are related to fluctuations in components of sickness in animals (e.”
The Sleep-Immune Crosstalk in Health and Disease (2019, background): “Over the last 30 yr, it has been well established that fever and sickness behavior in response to infection or inflammatory diseases are mediated by inflammatory mediators, including cytokines and PGs that signal to the brain (131, 487).”
Social regulation of gene expression in human leukocytes (2007, background): “... relationship between subjective social isolation and leukocyte transcriptional profiles observed here stems from a causal effect of social processes on gene expression (for example, via the neuroendocrine system), or whether differential gene expression in the immune system might instead drive v”
The Behavioral Immune System: Implications for Social Cognition, Social Interaction, and Social Influence (2016, background): “And the underlying neurophysiological mechanisms—which involve the immune system’s production of proinflammatory cytokines (Dantzer & Kelley, 2007)—are almost certainly distinct from those underlying the social psychological phenomena that we have reviewed above.”
Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factorα Signaling during Peripheral Organ Inflammation (2009, background): “Changes in behavior (termed sickness behaviors) that result from changes in central neural activity are often encountered during acute systemic infections and are felt to be an important adaptive mechanism for survival (Dantzer and Kelley, 2007).”