Bacterial Imprinting of the Neonatal Immune System: Lessons From Maternal Cells?

By P. Pérez, J. Doré, M. Leclerc, F. Levenez, J. Benyacoub, P. Serrant, I. Segura-Roggero, E. Schiffrin, A. Donnet-Hughes. Pediatrics, 2007

654 citations recorded by the source corpus.

Subfields: Ecology, Molecular Biology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/b4416333363abe4f8a6a5e8ac945f50d434f4cb0

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Citations in the corpus

The human milk microbiota: origin and potential roles in health and disease. (2013, background): “The authors speculated that this programs the eonatal immune system to recognize specific bacterial molecular atterns and to respond appropriately to pathogenic and comensal organisms [65].”
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment (2011, neutral): “Similarly, commensal bacteria have been proposed to translocate into the host mammary glands via MLN and Peyer’s patches in lactating mice (Hase et al, 2009; Perez et al, 2007; Sansonetti & Phalipon, 1999).”
Mom Knows Best: The Universality of Maternal Microbial Transmission (2013, background): “Interestingly, microbial translocation may even increase during pregnancy, as one study showed that pregnant mice were 60% more likely to harbor bacteria in their mesenteric lymph node (presumably brought there by dendritic cells) than nonpregnant mice [40].”
The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery. (2012, background): “In addition, the suggested transfer of bacteria present in the human gut to reach the mammary gland through an endogenous route (the so-called entero-mammary pathway) via the mucosal associated lymphoid system (30, 31) remains unclear.”
The Human Microbiome and Child Growth - First 1000 Days and Beyond. (2019, positive): “Gut microbial translocation increases during pregnancy [11].”
Worlds within worlds: evolution of the vertebrate gut microbiota (2008, background): “Related humans share microbiotas to a greater extent than unrelated humans who cohabi”
Role of the Microbiota in Immunity and inflammation (2014, background): “Bacterial translocation from the mouse gut is increased during pregnancy and lactation, and bacterially loaded dendritic cells in the milk have been proposed to contribute to neonatal immune imprinting by influencing the nature of the immune response toward commensal antigens (Perez et al., 2007).”
The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota (2017, background): “Interestingly, such adaptations may favor an increased bacterial translocation during late pregnancy and lactation (210, 217).”
The role of microorganisms in achieving the sustainable development goals (2018, background): “This helps the offspring in responding to pathogens and commensals appropriately (Kaplan et al., 2011; Perez et al., 2007).”
The composition of the gut microbiota throughout life, with an emphasis on early life (2015, background): “Interestingly, physiological bacterial translocation is highly increased during pregnancy and lactation in rodents (17).”