Body mass index in midlife and late‐life as a risk factor for dementia: a meta‐analysis of prospective studies

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National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease (2012, neutral): “In addition to the autosomal dominant PSEN1, PSEN2 and APP gene mutations or APOE ε4 allele, which clearly have a major impact on the accumulation of both plaques and CAA in AD, numerous other genetic variations [82,83] and environmental risk factors [84–86] have recently been described; the extent ”
Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population‐based perspective (2015, neutral): “[34] Anstey KJ, Cherbuin N, Budge M, Young J.”
A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on (2022, positive): “Epidemiologic studies have revealed an association between high body mass index (BMI) and an extensive range of chronic diseases such as Non Alcoholic Fatty Liver (NAFL), cardiovascular disease [1,2], diabetes mellitus [1], several malignancies [3,4], musculoskeletal diseases [5,6], chronic kidney d”
The Epidemiology of Obesity: A Big Picture (2015, background): “dementia, or any type of dementia by 35, 33, and 26 %, respectively; even higher risk is observed for obesity [123].”