Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population‐based perspective
By M. Baumgart, H. Snyder, Maria C. Carrillo, S. Fazio, Hye Kim, H. Johns. Alzheimer's & Dementia, 2015
1,502 citations recorded by the source corpus.
An estimated 47 million people worldwide are living with dementia in 2015, and this number is projected to triple by 2050. In the absence of a disease‐modifying treatment or cure, reducing the risk of developing dementia takes on added importance. In 2014, the World Dementia Council (WDC) requested the Alzheimer's Association evaluate and report on the state of the evidence on modifiable risk factors for cognitive decline and dementia. This report is a summary of the Association's evaluation, which was presented at the October 2014 WDC meeting. The Association believes there is sufficient evidence to support the link between several modifiable risk factors and a reduced risk for cognitive decline, and sufficient evidence to suggest that some modifiable risk factors may be associated with reduced risk of dementia. Specifically, the Association believes there is sufficiently strong evidence, from a population‐based perspective, to conclude that regular physical activity and management of cardiovascular risk factors (diabetes, obesity, smoking, and hypertension) reduce the risk of cognitive decline and may reduce the risk of dementia. The Association also believes there is sufficiently strong evidence to conclude that a healthy diet and lifelong learning/cognitive training may also reduce the risk of cognitive decline.
Subfields: Psychiatry and Mental health, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/d74c0e2c330774ab80b65169a14cda9b209f8bdd
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In Public Health, Environmental and Occupational Health
Citations in the corpus
- 2016 Alzheimer's disease facts and figures (2016, positive): “A recent report [46] evaluating the state of the evidence on the effects of modifiable risk factors on cognitive decline and dementia concluded that there is sufficiently strong evidence, from a population-based perspective, that regular physical activity andmanagement of cardiovascular risk factors”
- Racial and ethnic estimates of Alzheimer’s disease and related dementias in the United States (2015–2060) in adults aged ≥65 years (2018, background): “Education has a protective effect against dementia [40,41], but these estimates do not account for educational attainment because individual characteristics linked to socioeconomic status such as educational attainment and income are not reported in medical claims.”
- Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease (2017, background): “Specifically, grounded on a population-based perspective, the Alzheimer’s Association has identified regular physical exercise as one of the strategies to reduce the risk of cognitive decline and the development of dementia [224].”