Deciphering the transcriptional histone acetylation code for a human gene.
By T. Agalioti, Guoying Chen, Dimitris Thanos. Cell, 2002
695 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/b342e05c07154c71eb0311378b087a687ab31448
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In Molecular Biology
- Richard A. Young
- Keji Zhao
- Kairong Cui
- S. Khorasanizadeh
- Dustin E. Schones
- Chongzhi Zang
- C. D. Allis
- Weiqun Peng
Citations in the corpus
- The nucleosome: from genomic organization to genomic regulation. (2004, background): “In vitro, the recombinant, isolated Gcn5 HAT can acetylate peptide lysinehistone code for specifying downstream events (Strahl and Allis, 2000). substrates derived from histones H3 and H4.”
- Combinatorial patterns of histone acetylations and methylations in the human genome (2008, background): “Additionally, depletion of GCN5 or PCAF, but not CBP or p300, affects H4K8ac and H3K14a”
- Circuitry of nuclear factor κB signaling (2006, neutral): “This enhancer requires the assembly of an enhanceosome complex consisting of NF-kB, ATF2/c-Jun, and IRFs to recruit histone modification enzymes, effecting the repositioning of a core promoter nucleosome and recruitment of TFIID (83, 84).”
- Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones*S (2007, background): “Lys-8 of histone H4) provide a docking site to recruit a bromodomain-containing chromatin-remodeling enzyme SWI/SNF (23).”
- A chromatin landmark and transcription initiation at most promoters in human cells. (2007, background): “Acetylation of histone H3K9,14 is critical for the recruitment of transcription factor IID (TFIID), an initiating step in transcription (Agalioti et al., 2002), and should therefore be associated with genes that have recently initiated transcription.”
- Identification of multiple distinct Snf2 subfamilies with conserved structural motifs (2006, background): “These complexes may be recruited to specific regions of the genome through interactions with sequence-specific DNA-binding proteins [reviewed by (80)] or specific patterns of histone modifications (81,82) ISWI Iswi (Imitation SWI2) protein was identified in D.”
- Histone acetylation and deacetylation in yeast (2003, neutral): “Data for the in vivo specificity of bromodomains have come from Thanos and colleague”