Blood transfusion, independent of shock severity, is associated with worse outcome in trauma.
By D. Malone, J. Dunne, J. Tracy, A. Putnam, T. Scalea, L. Napolitano. Journal of Trauma, 2003
632 citations recorded by the source corpus.
Subfields: Biochemistry, Critical Care and Intensive Care Medicine, Emergency Medicine
View Paper: https://www.semanticscholar.org/paper/b2fa330b48ead2e9d5ba16ef3c0392ddcd247974
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In Biochemistry
In Critical Care and Intensive Care Medicine
Citations in the corpus
- The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition (2016, neutral): “Nevertheless, RBC transfusions have been shown in multiple studies to be associated with increased mortality [266–270], lung injury [270–272], increased infection rates [273, 274] and renal failure in trauma victims [269].”
- Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature* (2008, background): “(19) Prospective cohort 15,534 Increased mortality Risks outweigh benefits Yes Dunn et al.”
- Damage control resuscitation: directly addressing the early coagulopathy of trauma. (2007, background): “The safety of withholding PRBCs in hemodynamically stable patients has been demonstrated,(18) and the risks associated with blood transfusion are well described.(19,20) Further, massive transfusion in military and civilian casualties has been associated with an increased risk of death.”
- Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting* (2006, background): “Previous investigations have examined heterogenous patient populations (2, 4, 7, 9) such as mixed surgical, medical (2, 4), or trauma patients (7, 9).”
- Clinical review: Hemorrhagic shock (2004, background): “Blood transfusions have several negative side effects and have been associated with worse outcome in patients with trauma [48].”
- Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations. (2006, background): “The statistical association of massive transfusion for hemorrhagic shock with the development of MOF and with overall mortality may also be a reflection of immuno-modulation but this link has not yet been fully elucidated.(23,25,28,29)”
- Management of bleeding following major trauma: an updated European guideline (2010, neutral): “shown in multiple studies to be associated with increased mortality [230-234], lung injury [234-236], increased infection rates [237,238] and renal failure in trauma victims [233].”
- Management of bleeding and coagulopathy following major trauma: an updated European guideline (2013, neutral): “with increased mortality [213-217], lung injury [217-219],”
- Transfusion strategies for acute upper gastrointestinal bleeding. (2013, neutral): “Gastric varices 8/139 (6) 12/138 (9) 0.”