Transfusion strategies for acute upper gastrointestinal bleeding.

By C. Villanueva, A. Colomo, A. Bosch, M. Concepción, V. Hernández-Gea, C. Aracil, I. Graupera, M. Poca, C. Álvarez-Urturi, J. Gordillo and 4 more. New England Journal of Medicine, 2013

1,486 citations recorded by the source corpus.

Subfields: Biochemistry, Critical Care and Intensive Care Medicine, Gastroenterology

View Paper: https://www.semanticscholar.org/paper/25f9dbb0dff9e1109cc59b947215e3638f1859e9

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In Critical Care and Intensive Care Medicine

Citations in the corpus

Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases (2017, background): “A recent RCT including patients presenting with GI bleeding showed that a “restrictive” packed red blood cell (PRBC) transfusion strategy (initiating PRBC transfusion at a hemoglobin threshold of 7 g/dL and maintaining it at 7-9 g/dL) was associated with a significant decrease in mortality compared ”
UK guidelines on the management of variceal haemorrhage in cirrhotic patients (2000, result): “106 However, it should be noted that these results were from a single Spanish centre, which was a tertiary unit for variceal bleeding, where all patients underwent endoscopy within 6 h. Nonetheless, a restrictive transfusion policy has been recommended for some time 1 and there is now good evidence…”
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. (2018, background): “transfusion strategy is adequate in most patients with acute GI bleeding, with a haemoglobin threshold for transfusion of 7 g/dl and a target range after transfusion of 7 to 9 g/dl [201].”
Liberal or restrictive transfusion after cardiac surgery. (2015, background): “42 In contrast, a large trial involving patients with hip fracture, 43 in which 63% of the participants had cardiovascular disease, showed no benefit from restrictive transfusion, and a more recent feasibility trial of transfusion thresholds in patients with unstable coronary disease (myocardial…”
The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition (2016, background): “and 9 g/dL) are as safe as, or safer than, liberal strategies (thresholds ≥9 g/dL) [260–263], with the possible exception of patients following cardiac surgery [264] or with”