Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme.
By A. Vertegel, R. W. Siegel, Jonathan S. Dordick. Langmuir, 2004
808 citations recorded by the source corpus.
Subfields: Biomaterials, Electronic, Optical and Magnetic Materials, Surfaces, Coatings and Films
View Paper: https://www.semanticscholar.org/paper/b1b0b741aeed8453ba7c8d4bd1f40f4501adce6a
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In Biomaterials
In Electronic, Optical and Magnetic Materials
In Surfaces, Coatings and Films
Citations in the corpus
- Enzyme Immobilization: An Overview on Nanoparticles as ImmobilizationMatrix (2015, methodology): “Enzymatic immobilization on Au and Ag nanoparticles have been studied using either as whole cells or isolated enzymes, which include lysozyme [61], glucose oxidase [62], aminopeptidase [63], as well as alcohol dehydrogenase [64].”
- Understanding biophysicochemical interactions at the nano-bio interface. (2009, background): “In a given medium, the most important nanoparticle characteristics that determine the surface properties are the material's chemical composition, surface functionalization, shape and angle of curvature, porosity and surface crystallinity, heterogeneity, roughness, and hydrophobicity or hydrophilicit”
- Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation. (2006, background): “Nanoparticles will adsorb proteins, resulting in changes to the surface of the particle as well as changes in the structure and activity of the adsorbed protein (Jiang et al., 2005; Mueller et al., 2001; Vertegel et al., 2004).”
- Potential applications of enzymes immobilized on/in nano materials: A review. (2012, background): “Gold nanoparticles can be easily and efficiently functionalized with thiolated molecules and carboxylic groups, which in turn, are conjugated with amino groups of the proteins (Jun et al., 2001; Vertegel et al., 2004).”
- Interactions of graphene and graphene oxide with proteins and peptides (2013, background): “It has been illustrated that the composition, morphology (including the dimensions), and surface functionalities of the solid substrates play important roles in regulating their interaction with enzyme molecules, the conformation of the enzymes, and the catalytic activity of the immobilized enzymes ”
- Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle (2013, background): “Silica NPs (100 nm) were capable of inducing greater loss of structure and function for the protein lysozyme as compared to 4 nm sized particles [81].”