Long-term multiple color imaging of live cells using quantum dot bioconjugates

By J. Jaiswal, H. Mattoussi, J. Mauro, S. Simon. Nature Biotechnology, 2003

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Semiconductor Quantum Dots in Chemical Sensors and Biosensors (2009, background): “This increases the photostability of the core and the quantum yield, so that core-shell structured QDs are more favourable for fluorescence-based applications [7].”
Self-assembled nanoscale biosensors based on quantum dot FRET donors (2003, background): “QDs also have exceptional photochemical stability and relatively high quantum yield”
A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors (2005, methodology): “Similarly, HeLa and Dictyostelium discoideum cells treated with 400–600 nM concentrations of CdSe/ZnS QDs capped with DHLA were observed to remain stably labeled for more than a week with no detectable effects on cell morphology or physiology (Jaiswal et al. 2003).”
Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy (2004, background): “QDs are also virtually resistant to photobleaching and are as bright as the best-known organic fluorophore”