AP-1 in mouse development and tumorigenesis

By W. Jochum, E. Passegué, E. Wagner. Oncogene, 2001

761 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. (2008, neutral): “…as AP-1 and suggest that this differential recruitment could also play an important role in its well-known cell-lineage differential activities (Jochum et al., 2001) The functional importance of FoxA1 cell-specific recruitment described above raises the question as to how FoxA1 is able to bind…”
Transcriptional regulation by calcium, calcineurin, and NFAT. (2003, background): “6). p21SNFT binds NFAT mainly as a heterodimer with Jun (Bower et al. 2002), and it is therefore expected that the binding interactions are mostly mediated by Jun and will be similar to that seen in the NFAT/ Fos–Jun/DNA complex.”
The control of chondrogenesis (2006, background): “Several genetic studies have provided insight into the roles of AP-1 family members, including c-Fos, Fra1, Fra2, c-Fos, FosB, JunB, and ATF-2, in skeletal development in vivo [Grigoriadis et al., 1993; Reimold et al., 1996; Jochum et al., 2000; Jochum et al., 2001; Hess et al., 2003; Karreth et al.”