The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

By Ryan T. Phan, R. Dalla-Favera. Nature, 2004

711 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/b0deaa148b6b5b0fca4b414bb2ab019a6d8db80c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Peter A. Jones
2. Manel Esteller
3. Carlo Maria Croce

In Molecular Biology

1. Peter A. Jones
2. G. Liang
3. Gerda Egger
4. R. Dalla-Favera
5. Gerhard A. Coetzee
6. U. Klein
7. Manel Esteller
8. S. Baylin

In Oncology

1. R. Dalla-Favera
2. Peter A. Jones
3. U. Klein

Citations in the corpus

• Double-hit B-cell lymphomas. (2011, neutral): “Bertrand et al40 2007 10/17 (59) 1/10 (10) 58 (45-81) 7/10 (70) NA† NA NA NA 5/9 (56)‡”
• Mechanism and regulation of class switch recombination. (2008, result): “Protection from cell death in GC cells had previously been thought to be due to the downregulation of p53 by Bcl-6, as demonstrated in Ramos cells (213), but Ranuncolo et al.”
• Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. (2006, background): “Moreover, BCL6 suppresses p53 expression and modulates DNA damage-induced apoptotic responses in germinal center B cells (Phan and Dalla-Favera, 2004).”
• Germinal centres: role in B-cell physiology and malignancy (2008, background): “Notably, the sensing of and response to DNA damage are specifically suppressed in centroblast”