On the importance and mechanisms of burst release in matrix-controlled drug delivery systems.

By Xiao Huang, C. Brazel. Journal of Controlled Release, 2001

1,629 citations recorded by the source corpus.

Subfields: Molecular Medicine, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/ae481c4c0f60e8b2bf125a68a6c16a4dc1b8cb8e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Medicine

1. Chien-Chi Lin
2. Ali Khademhosseini
3. A. Metters
4. M. Oyen

In Pharmaceutical Science

1. Ali Khademhosseini
2. Chien-Chi Lin
3. A. Metters

Citations in the corpus

• Hydrogels in controlled release formulations: network design and mathematical modeling. (2006, background): “One of the unique challenges facing microscaled matrix delivery systems is burst release due to the high surface-to-volume ratio of these particulate systems [174,175].”
• Drug Delivery Systems and Materials for Wound Healing Applications (2018, positive): “In phase 3, a faster release is observed due to erosion of the drug carrier [154, 220, 221].”