Hydrogels in controlled release formulations: network design and mathematical modeling.

By Chien-Chi Lin, A. Metters. Advanced Drug Delivery Reviews, 2006

1,713 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Drug Release Kinetics and Transport Mechanisms of Non-degradable and Degradable Polymeric Delivery Systems (2010, background): “Lin CC, Metters AT.”
Microwave-assisted polymer synthesis (MAPS) as a tool in biomaterials science: How new and how powerful (2011, background): “, proteins) [215,216], and cell culture and tissue engineering [217].”
Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds (2014, neutral): “where C is the concentration of the free drug, D is its diffusivity, and Kb is the ratio of the concentration of available binding sites to the dissociation constant Kd [61].”
Design properties of hydrogel tissue-engineering scaffolds (2011, background): “Diffusion is the most widely applicable mechanism to describe drug release from hydrogels [23].”
Chitosan-based hydrogels for controlled, localized drug delivery. (2010, background): “degradation of pendent chains or during surface erosion or by bulk degradation of the polymers [51].”
pH Sensitive Hydrogels in Drug Delivery: Brief History, Properties, Swelling, and Release Mechanism, Material Selection and Applications (2017, background): “If the rate of drug release exceeds the rate of swelling then drug release follows a swelling controlled mechanism [54].”