The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

By Alexandre Dias, D. Bouvier, T. Crépin, A. McCarthy, D. Hart, F. Baudin, Stephen Cusack, R. Ruigrok. Nature, 2009

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mRNA capping: biological functions and applications (2016, positive): “The endonuclease activity of PA then cleaves the first 10–15 nt of the capped RNA, which is then used to prime viral mRNA transcription (133–136) (Table 1).”
An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response (2012, background): “Such a frameshift event would produce a 29kDa fusion protein, termed PAX, comprising the N-terminal endonuclease domain of PA (4,5) and, in most isolates, a novel 61 amino acid C-terminus from the X-ORF (Fig 1C).”
Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality (2015, background): “This included five PLOS Genetics | DOI:10.1371/journal.pgen.1005310 July 1, 2015 5 / 27 substitutions in the endonuclease active site (E80V, E80G, E80K, E119V, K134) [20, 21], and six substitutions in the cRNA promoter binding site (E166D, R170W, R170M, R170K, T173I, T173A) [18, 61].”