Proteoglycans : structure, biology, and molecular interactions

By R. Iozzo. 2000

177 citations recorded by the source corpus.

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Cylindrical molecular brushes: Synthesis, characterization, and properties (2008, background): “Among the many amazing biomolecules at work in nature is a group known as proteoglycans [1–3].”
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans (2015, background): “The heparan sulfate chains of perlecan and the protein core can be cleaved by heparanase and various proteases [110–112], respectively, releasing various pro-angiogenic factors [113].”
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice (2021, background): “Isolation of an anti-GPC2 antibody with undetectable binding to normal vital organs Although glypican members share 25% amino acid similarity, their C-terminal regions close to the cell membrane are low in sequence similarity.(17) It has been indicated that CARs targeting membrane-proximal epitopes ”