Can bioactivity be tested in vitro with SBF solution?

By M. Bohner, J. Lemaître. Biomaterials, 2009

892 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

The role of prenucleation clusters in surface-induced calcium phosphate crystallization. (2010, methodology): “Although the application of SBF to predict the in vivo bioactivity of implants has been a subject of discussio”
Bioactive calcium phosphate materials and applications in bone regeneration (2019, background): “[68, 69] and the surface of HAP can act as a nucleating site for bone minerals in body fluids [42, 70].”
Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review (2011, background): “In bone tissue engineering “a bioactive material is a material on which bone-like hydroxyapatite will form selectively after it is immersed in a serum-like solution” [22].”
Bioactive glass in tissue engineering (2011, positive): “However, this narrow definition of bioactivity has been called into question recently [50].”
Mineralized structures in nature: Examples and inspirations for the design of new composite materials and biomaterials (2010, background): “on its surface upon immersion in SBF [49-51].”