Intraplaque hemorrhage and progression of coronary atheroma.

By F. Kolodgie, H. Gold, A. Burke, David R. Fowler, H. Kruth, D. Weber, A. Farb, L. Guerrero, M. Hayase, R. Kutys and 3 more. New England Journal of Medicine, 2003

1,513 citations recorded by the source corpus.

Subfields: Immunology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/adadac42c7f919bdd6e5d5b9e9ea1c2639219098

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Erling Falk
2. J. Bentzon
3. Renu Virmani
4. S. Jackson
5. A. Tedgui
6. Z. Mallat
7. F. Otsuka
8. A. Poole

In Pulmonary and Respiratory Medicine

1. Erling Falk
2. Renu Virmani
3. J. Bentzon
4. F. Otsuka

Citations in the corpus

• Immunity, atherosclerosis and cardiovascular disease (2013, background): “be a proinflammatory factor, increasing the risk of plaque rupture [89,90].”
• Cytokines in atherosclerosis: pathogenic and regulatory pathways. (2006, background): “Also determinant in the understanding of the pathogenesis of atherosclerosis were the works by the pathologists Michael Davies (158, 159) and Erling Falk (198), later confirmed and extended by the group of Renu Virmani (704), in their quest for the causes of acute coronary syndromes.”
• Platelets in Inflammation and Atherogenesis (2015, background): “Moreover, red blood cells get stuck in the plaque liberating hemoglobin and iron (131).”
• Arterial thrombosis—insidious, unpredictable and deadly (2011, background): “Similarly, coagulation reactions linked to fibrin generation may also contribute to the rapid progression of atherosclerotic lesion”
• Mechanisms of plaque formation and rupture. (2014, background): “The necrotic core may be characterized as early or late with the former showing some presence of hyaluronan and versican with macrophage infiltration, whereas in the latter, no matrix at all is observed.(48) When a necrotic core is present, the lesion is a fibroatheroma (Figure 1D).”
• Atherosclerotic Plaque Progression and Vulnerability to Rupture: Angiogenesis as a Source of Intraplaque Hemorrhage (2005, background): “Focal collections of T-cell– and macrophage-derived angiogenic factors contribute to: (1) the arborization of vasa vasorum around the necrotic core; (2) the formation of immature vessels; and (3) loss of basement membrane around functional capillaries.”
• Update on acute coronary syndromes: the pathologists' view. (2013, background): “97 Such intraplaque bleedings are common(8) and may expand the necrotic core, causing rapid progression of the lesion.(90) Another common source of plaque haemorrhage is extravasation of blood through a ruptured fibrous cap,(26) called an intraintimal thrombus by Davies.”