Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.
By H. Bartsch, Nair Uj, A. Risch, M. Rojas, H. Wikman, K. Alexandrov. Cancer Epidemiology, Biomarkers and Prevention, 2000
614 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/ad7044e1f7ffc19d612e1ad2da162fce9dc9e401
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Citations in the corpus
- Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight. (2002, background): “Major classes of carcinogens present in cigarette smoke are converted into DNA-reactive metabolites by cytochromeP450–relatedenzymesandsome cytochrome P450 variants have been associated with increased risk of various cancers.(12) On the other hand, the GSTT1 enzyme is important in protecting against”