Clinical transplantation of a tissue-engineered airway.

By P. Macchiarini, P. Jungebluth, T. Go, Adelaide Asnaghi, L. Rees, T. Cogan, A. Dodson, J. Martorell., Silvia Bellini, P. Parnigotto and 5 more. The Lancet, 2008

1,379 citations recorded by the source corpus.

Subfields: Pulmonary and Respiratory Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/abac4139ea0757dfea6d35cc785a3ffa416844a0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Pulmonary and Respiratory Medicine

1. J. Rock
2. E. Morrisey
3. B. Stripp
4. B. Hogan
5. C. E. Barkauskas
6. S. Randell

In Surgery

1. Chaomei Chen
2. Meen Chul Kim
3. Rachael Dubin
4. B. Hogan

Citations in the corpus

• Engineering hydrogels as extracellular matrix mimics (2010, neutral): “There are examples of successful clinical translations of engineered tissues [77–81], such as tissue engineered bladders [78], lung tracheal segments [82] and the lamina propria of human vocal fold developed from highly elastic gels of double-crosslinked hyaluronic acid microparticles [83].”
• Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications (2017, methodology): “Decellularized ECMhas been successfully used to recreate various types of tissues and organs including blood vessel [23–25], heart valve [26, 27], cornea [28–30], trachea [31], esophagus [32], urinary bladder [33], kidney [34, 35], liver [36–39], lung [40, 41], and heart [42, 43].”
• Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling (2010, background): “The clinical use of such reconstructed tissue for a patient with airway stenosis has been recently demonstrated (Macchiarini et al., 2008).”
• Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. (2012, methodology): “Perhaps more importantly, this approach has been successfully used in humans to correct large airway defects (16, 17).”
• The extracellular matrix at a glance (2010, background): “To overcome this issue, tissue engineers and biomaterial specialists have generated denuded ECM scaffold from various tissues (Macchiarini et al., 2008).”
• Green composites: A review of material attributes and complementary applications (2014, positive): “A trachea has been successfully grown using this technique and the subsequent transplant proved ground breaking since the procedure allowed the patient an immunosuppressant-free life, unlike normal transplantees [72].”