An abundance of X-linked genes expressed in spermatogonia

By P. Wang, J. McCarrey, Fang Yang, D. Page. Nature Genetics, 2001

797 citations recorded by the source corpus.

Subfields: Genetics, Reproductive Medicine

View Paper: https://www.semanticscholar.org/paper/aab9b0ee11de8ed6b966e2f91def4d3534170708

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. B. Charlesworth
2. Kevin R. Thornton
3. J. Turner
4. Eric E. Schadt
5. A. Arnold
6. G. S. V. Doorn
7. Aldons J. Lusis
8. Brandon S. Gaut

In Reproductive Medicine

1. J. Turner
2. A. Arnold
3. Aldons J. Lusis

Citations in the corpus

• Tissue-specific expression and regulation of sexually dimorphic genes in mice. (2006, background): “Previous studies on sex and reproductive tissues suggested that sexually dimorphic genes are concentrated on sex chromosomes, particularly the X chromosome (Saifi and Chandra 1999; Wang et al. 2001; Arnold 2004; Vawter et al. 2004).”
• A genomic and functional inventory of deubiquitinating enzymes. (2005, neutral): “VCIP135 Unknown Golgi disassembly Wang et al. (2004)”
• The X chromosome in immune functions: when a chromosome makes the difference (2010, background): “However, if the sex-biased fitness effects are strong, expression of male-beneficial genes may become restricted to male-specific tissue”
• Evolution on the X chromosome: unusual patterns and processes (2006, background): “Initial reports in rodents suggested that the X chromosome had an excess of male-biased gene”
• The origin of new genes: glimpses from the young and old (2003, background): “The strong correlation between the timing of expression and the chromosomal locations of spermatogenesis gene”
• Intralocus Sexual Conflict (2009, background): “In mice, genes preferentially expressed in ovary, placenta, or early spermatogenesis are overrepresented on the X chromosome, whereas genes expressed during late spermatogenesis are nearly absent (Wang et al. 2001; Khil et al. 2004; Divina et al. 2005), presumably in response to (or allowing for) ea”
• Meiotic sex chromosome inactivation (2007, positive): “One study (Wang et al., 2001) has revealed that a disproportionately large number of spermatogonial-specific transcripts originate from the X and Y chromosomes.”
• The X and Y Chromosomes Assemble into H2A.Z, Containing Facultative Heterochromatin, following Meiosis (2006, background): “Z expression prior to pachytene, gene expression is high on autosomes and sex chromosomes (29, 52, 65).”