The role and regulation of programmed cell death in plant–pathogen interactions

By J. Greenberg, N. Yao. Cellular Microbiology, 2004

713 citations recorded by the source corpus.

It is commonly known that animal pathogens often target and suppress programmed cell death (pcd) pathway components to manipulate their hosts. In contrast, plant pathogens often trigger pcd. In cases in which plant pcd accompanies disease resistance, an event called the hypersensitive response, the plant surveillance system has learned to detect pathogen‐secreted molecules in order to mount a defence response. In plants without genetic disease resistance, these secreted molecules serve as virulence factors that act through largely unknown mechanisms. Recent studies suggest that plant bacterial pathogens also secrete antiapoptotic proteins to promote their virulence. In contrast, a number of fungal pathogens secrete pcd‐promoting molecules that are critical virulence factors. Here, we review recent progress in determining the role and regulation of plant pcd responses that accompany both resistance and susceptible interactions. We also review progress in discerning the mechanisms by which plant pcd occurs during these different interactions.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/aa37ecbea88f31a80b8758324e5c9531e91ea324

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Citations in the corpus

Biological functions of antioxidants in plant transformation (2008, background): “The most extensively studied form of plant PCD is HR to pathogen infection (Greenberg and Yao 2004; Soosaar et al. 2005).”
Involvement of calcium oxalate degradation during programmed cell death in Theobroma cacao tissues triggered by the hemibiotrophic fungus Moniliophthora perniciosa (2007, background): “HR is a PCD-related process characterized by a rapid host response to pathogen infection that causes growth inhibition [6] and induces the secretion of pathogen-induced components [7].”
Rhizobacteria-induced systemic resistance (2009, background): “This hypersensitive response (HR) is thought to benefit the plant by restricting pathogen access to water and nutrients and is correlated with an integrated set of physiological and metabolic alterations that are instrumental in impeding further pathogen ingress, among which exists a burst of oxidat”
The role of the mitochondrion in plant responses to biotic stress (2007, positive): “Upon recognition of a pathogen, plants mount a resistance response meant to cease pathogen growth and disease development (Dangl and Jones 2001, Greenberg and Yao 2004, Lam et al. 2001).”
Redox Regulation in Photosynthetic Organisms: Signaling, Acclimation, and Practical Implications (2009, positive): “…facilitates the pre-acclimation of photosynthetic tissues to high light is distinct from that of pathogen-related systemic acquired resistance (359), these studies show that PAD4, EDS1, and MPK4 interact with LSD1 in signal pathways, leading to PCD (434) and with some responses to EEE (259, 260).”
Arabidopsis PEN3/PDR8, an ATP Binding Cassette Transporter, Contributes to Nonhost Resistance to Inappropriate Pathogens That Enter by Direct Penetration[W][OA] (2006, background): “Cell death in response to pathogen attack is often associated with the activation of the SA defense pathway (Greenberg and Yao, 2004).”
Genetic linkage maps of two interspecific grape crosses (Vitis spp.) used to localize quantitative trait loci for downy mildew resistance (2011, background): “Resistance mechanisms so far elucidated (Kortekamp et al. 1998; Kortekamp and Zyprian 2003; Kortekamp 2006; Allegre et al. 2007) include physical barriers such as hairs and stomatal closure, the accumulation of phenolic antimicrobial compounds, increased peroxidase activity, the accumulation of path”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “The recognition and attenuation of Avr proteins by plant R-proteins results in effector-triggered immunity (ETI), which is usually manifest in a hypersensitive response (HR; Greenberg and Yao, 2004).”
Roles of reactive oxygen species in interactions between plants and pathogens (2008, background): “2001), although it has been questioned whether this is a general phenomenon (Greenberg and Yao 2004).”