Gene therapy: twenty-first century medicine.

By Inder M. Verma, M. Weitzman. Annual Review of Biochemistry, 2005

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Gene therapy clinical trials worldwide to 2017: An update (2018, background): “By contrast, viral systems, which are commonly modified to render them replication‐incompetent, are markedly more efficient and exploit favourable aspects of virus biology.(121,122) Depending on the nature of the modification required, however, transient delivery of nucleic acids, oligonucleotides, ”
The present and future of nanotechnology in human health care. (2007, background): “Gene therapy is a recently introduced method for treatment or prevention of genetic disorders by correcting defective genes responsible for disease development based on the delivery of repaired genes or the replacement of incorrect ones [54-57].”
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration (2006, background): “Lentiviral vectors transduce hematopoietic stem cells with high efficiency and minimal manipulation, leading to robust and stable expression in their progen”
Genetic dissection of neural circuits. (2008, neutral): “After Verma and Weitzman (2005).”