Scar-free healing: from embryonic mechanisms to adult therapeutic intervention.
By M. Ferguson, S. O'Kane. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2004
837 citations recorded by the source corpus.
Subfields: Rehabilitation, Surgery, Urology
View Paper: https://www.semanticscholar.org/paper/aa0448ba3ad47fa7cb7d30a83633c908fb36ed5a
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Citations in the corpus
- Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration (2007, background): “…altered inflammatory response and skin morphogenesis, the growth factor profile of a healing embryonic wound is very different qualitatively, quantitatively and temporally compared with an adult wound (Whitby & Ferguson 1991b; O’Kane & Ferguson 1997; Cowin et al. 2001a,b; Ferguson & O’Kane 2004).”
- Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration (2020, background): “When excessive scarring occurs, there is an imbalance between biosynthesis and degradation, mediated by apoptosis and ECM degradation, and this dysfunction leads to a persistent inflammatory phase, a prolonged proliferation phase and reduced remodeling [32].”
- Progress and opportunities for tissue-engineered skin (2007, background): “on understanding the role of the transforming growth factor-β family in wound healing and scar formation is now being developed into a therap”
- Inflammation in Chronic Wounds (2016, background): “However, in modern, sterile surgical wounds, such a response is unwarranted and unwanted—not only does it delay healing, scars create unaesthetically-pleasing, weaker skin [39].”
- Mechanobiology of tendon. (2006, background): “TGF-b2 functions similarly to TGF-b1; however, TGFb3 has been shown to improve tissue scarring (Ferguson and O’Kane, 2004; Shah et al., 1995).”