Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

By David A. Fidock, Takashi Nomura, A. Talley, R. Cooper, S. Dzekunov, M. Ferdig, L. Ursos, A. Sidhu, Bronwen Naudé, K. Deitsch and 4 more. Molecules and Cells, 2000

1,442 citations recorded by the source corpus.

Subfields: Molecular Medicine, Oncology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/a91c0a704d802e4d4c61992158a0b31a40c1a597

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. R. Ridley
2. John C. Wootton
3. X. Su
4. Jianbing Mu
5. M. Ferdig
6. D. Baruch
7. A. Magill
8. Xiaorong Feng

Citations in the corpus

• Medical need, scientific opportunity and the drive for antimalarial drugs (2002, background): “falciparum resistance to chloroquine, and potentially to some other 4-aminoquinolines, is linked to the putative chloroquine resistancetransporter gene PfCRT”
• Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum (2002, background): “, here we show that the level of genetic diversity varies substantially among different regions of the parasite genome, revealing extensive linkage disequilibrium surrounding the key CQR gene pfcrt”