Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum
By John C. Wootton, Xiaorong Feng, M. Ferdig, R. Cooper, Jianbing Mu, D. Baruch, A. Magill, X. Su. Nature, 2002
748 citations recorded by the source corpus.
Subfields: Immunology, Parasitology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/60a32ef624be7fedfc9b874b4c2ffe3e61aafa72
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In Immunology
Citations in the corpus
- Combining population genomics and quantitative genetics: finding the genes underlying ecologically important traits (2008, background): “…in maize during domestication (Vigouroux et al., 2002), genes for coat color and shortened limbs in dog breed formation (Pollinger et al., 2005), chloroquine resistance in the malaria-inducing parasite Plasmodium falciparum (Wootton et al., 2002) and warfarin resistance in rats (Kohn et al., 2003).”
- Genomic scans for selective sweeps using SNP data. (2005, background): “The elimination of standing variation in regions linked to a recently fixed beneficial mutation is known as a “selective sweep” and has recently been the focus of much theoretical and empirical attention (e.g., Fay and Wu 2000; Parsch et al. 2001; Harr et al. 2002; Kim and Stephan 2002; Przeworski 2”
- A molecular marker of artemisinin-resistant Plasmodium falciparum malaria (2013, methodology): “The exomesof F32-ART5 andF32-TEMwere compared after excluding (1) genes fromhighly variable,multi-gene families (var, rifin and stevor), (2) positions with coverage lower than 25% of the mean coverage of the parasite line, (3) single-nucleotide polymorphisms (SNPs) found to be mixed in F32-ART5, giv”
- INVITED REVIEW: Using genome scans of DNA polymorphism to infer adaptive population divergence (2005, background): “…& Schlötterer 2004; Storz et al. 2004), comparisons between affected vs. nonaffected populations in a case–control study design (Kohn et al. 2000, Wootton et al. 2002; Kohn et al. 2003; Nair et al. 2003), or comparisons between a domesticated species and its wild progenitor (Vigouroux et al.…”
- Simulated climate change provokes rapid genetic change in the Mediterranean shrub Fumana thymifolia (2008, background): “This approach has been used recently to identify evolutionary responses to disease control agents (Wooton et al., 2002) and during domestication of ancestral crop varieties (Vigouroux et al., 2002), adaptation along environmental gradients (Wilding et al., 2001; Campbell & Bernatchez, 2004; Bonin…”
- A Systematic Map of Genetic Variation in Plasmodium falciparum (2006, neutral): “The trough at pfcrt is likely to be due to the strong selective pressure on pfcrt, and is consistent with the observation that FCB and Dd2 have different alleles of pfcrt even though published SNP data also shows disequilibrium in surrounding regions [5].”