A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening

By K. Manning, M. Tör, M. Poole, Yiguo Hong, A. Thompson, G. King, James J. Giovannoni, G. Seymour. Nature Genetics, 2006

1,207 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/a85acf214031e24381a478b86c90687e18b5da56

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. M. Bouzayen
2. B. Cara
3. A. Latché
4. J. Pech
5. M. Fraga
6. James J. Giovannoni
7. R. Feil
8. B. Pogson

In Plant Science

1. M. Bouzayen
2. B. Cara
3. A. Latché
4. J. Pech
5. S. Zhong
6. M. Fraga
7. James J. Giovannoni
8. R. Feil

Citations in the corpus

• Mechanism of Fruit Ripening (2010, background): “The Colorless non-ripening (Cnr) mutant is a dominant mutant corresponding to an epigenetic mutation that alters the methylation of the promoter of a SPB box transcription factor ( Manning et al. 2006 ).”
• Transgenerational Epigenetic Inheritance: myths and mechanisms (2014, neutral): “Epigenetic variants in garden varieties, such as peloric flowers in toad flax and nonripening tomatoes, also have unstable phenotypes associated with methylation changes near genes, in a nearby transposon in at least one case (Cubas et al., 1999; Manning et al., 2006).”
• Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “Recent genetic analyses of large data sets generated by high-throughput profiling of mapping populations with various ‘-omics’ procedures allow genetic integration of several levels of molecular mechanisms regulating phenotypic variation (Chevalier et al., 2004; Manning et al., 2006; West et al., 20”
• Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics (2016, background): “Naturally occurring epialleles such as the peloric variant of toadflax, Linaria vulgaris (91), and the colorless nonripening (CNR) locus from tomato (92) along with genome-wide studies (93, 94), natural variation (95, 96), and analysis of epigenetic recombinant inbred lines (97–99) demonstrate the s”
• Genetics and control of tomato fruit ripening and quality attributes. (2011, background): “SPBP targets include MADS-box genes and the tomato ortholog of the Arabidopsis FRUITFUL (FUL) MADS-box gene, TDR4, is substantially reduced in Cnr, suggesting that it may be a CNR target and a regulator through which CNR exerts its effects (50).”
• Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening (2013, background): “(3) DNA methylation rate in each sequence context.”
• Molecular biology of ethylene during tomato fruit development and maturation (2008, background): “LeMADS-RIN and is a member of the SEPALATA subfamily of MADS genes [20], while the Cnr mutation resulted from a dominant epigenetic alteration in the promoter of a SQUAMOSA promoterbinding protein (SBP) [112].”