The small-molecule approach to biology

By Stefan Schreiber. 2003

204 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/a7ebc54ce4575f363c9418a5fb41d4f1e161417d

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1. H. Pajouhesh
2. G. R. Lenz

Citations in the corpus

• A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. (2006, unknown): “Many of these molecules have found widespread use as biological probes, often because the speed, dose-dependence, and reversibility of their activities provide a useful complement to genetic techniques (Schreiber, 2003).”
• Medicinal chemical properties of successful central nervous system drugs (2005, background): “The NIH effort is designed to generate a set of drug-like molecules that are targeted to probe the intersection of chemistry and biology space, albeit dilutely.(27) The growth of computing power allowed the development of in silico approaches that are based on laboratory-derived data sets.”