mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.

By M. Morita, Simon-Pierre Gravel, Valérie Chénard, Kristina Sikström, Liang Zheng, T. Alain, V. Gandin, D. Avizonis, Meztli Arguello, Chadi Zakaria and 9 more. Cell Metabolism, 2013

787 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4c06f8b20174c696b41d2dbe3ff9c6e1ac4ecde7

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In Molecular Biology

1. W. Cui
2. Jason S. L. Yu

Citations in the corpus

• Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination (2016, background): “On the other hand, mTORC1 positively regulates mitochondrial function and oxidative metabolism by selectively promoting translation of nucleus-encoded mitochondria-related mRNAs (Morita et al., 2013).”
• Mitochondrial dysfunction: mechanisms and advances in therapy (2024, background): “118 On the other hand, mTOR activity is closely related to mitochondrial metabolism.”