Identifying Autism Loci and Genes by Tracing Recent Shared Ancestry

By Eric M. Morrow, S. Yoo, S. Flavell, Tae-Kyung Kim, Yingxi Lin, R. Hill, N. M. Mukaddes, S. Balkhy, G. Gascon, A. Hashmi and 15 more. Science, 2008

766 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a703fb90ef9de70a7f4139420837ef13fd61e591

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. Simon Baron-Cohen
2. Daniel H. Geschwind
3. Michael V. Lombardo
4. Catherine Lord
5. Bhismadev Chakrabarti
6. Bonnie Auyeung
7. Rebecca C. Knickmeyer
8. Emma Ashwin

In Genetics

1. Michael V. Lombardo
2. Catherine Lord
3. Bhismadev Chakrabarti
4. Bonnie Auyeung
5. Simon Baron-Cohen
6. Eric Fombonne
7. Michael E. Greenberg
8. Rebecca C. Knickmeyer

In Molecular Biology

1. R. J. Kelleher
2. Paul L. Greer
3. Catherine Lord
4. Michael E. Greenberg
5. Daniel H. Geschwind
6. Brian J. O'Roak
7. Mark F. Bear
8. Shrikant M. Mane

Citations in the corpus

• From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function. (2008, background): “lineages identified two large genomic deletions that cosegregated with autism (Morrow et al., 2008).”
• The autistic neuron: troubled translation? (2008, background): “In a recent human genetic study, ASD-linked deletion mutations affected several genes whose expression is stimulated by neuronal activity, further arguing that defects in synaptic activityinduced gene expression contribute to ASD pathogenesis (Morrow et al., 2008).”
• Rare de novo and transmitted copy-number variation in autistic spectrum disorders. (2011, neutral): “Rare Homozygous Deletions Although our focus has been on rare variants that contribute to phenotypes in a dominant fashion, it has been documented that some autism can result from the combined action of recessive alleles (Morrow et al., 2008).”
• Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. (2011, background): “, 2009), homozygosity mapping (Morrow et al., 2008), and common variant findings (Wang et al.”
• AutDB: a gene reference resource for autism research (2008, background): “The first rare single gene mutation in ASD was reported in 2003 (18), however, in the last two years with the application of genomic technologies, a steady stream of single gene mutations in ASD is reported in the scientific literature (15,20).”
• Heritability in the Era of Molecular Genetics: Some Thoughts for Understanding Genetic Influences on Behavioural Traits (2011, background): “Their involvement is increasingly suspected in major behavioural disorders such as schizophrenia and autism (Sebat et al., 2007; International Schizophrenia Consortium, 2008; Kumar et al., 2008; Morrow et al., 2008; Stefansson et al., 2008; Walsh et al., 2008; Xu et al., 2008).”