Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human.

By É. Mezey, Zsuzsanna E. Tóth, D. Cortright, Michelle K. Arzubi, J. Krause, R. Elde, A. Guo, P. Blumberg, A. Szallasi. Proceedings of the National Academy of Sciences of the United States of America, 2000

853 citations recorded by the source corpus.

Subfields: Physiology, Sensory Systems, Social Psychology

View Paper: https://www.semanticscholar.org/paper/a69bafb9a8fd58c1e4e416dc464905dd05a7dcfe

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Physiology

1. R. Ross
2. D. Julius
3. Clifford J. Woolf

In Sensory Systems

1. R. Ross
2. S. R. Eid
3. D. Julius
4. Clifford J. Woolf
5. R. Pertwee

Citations in the corpus

• Induction of vanilloid receptor channel activity by protein kinase C (2000, background): “However, considerable attention has been focused on identifying other signalling pathways in VR activation; it is known that VR1 is also expressed in non-sensory tissu”
• Anandamide and vanilloid TRPV1 receptors (2003, background): “TRPV1 receptors have been thought to be primarily associated with the peripheral nervous system and in particular, primary afferent fibres, yet PCR studies show that TRPV1 mRNA is present in brain tissue and is especially high in the CA1 and CA3 regions of the hippocampus (Mezey et al., 2000).”
• Paracetamol: new vistas of an old drug. (2006, background): “Interestingly, in brain regions with high expression of FAAH, both TRPV1 and CB1 receptors are also found (mesencephalic trigeminal nucleus, primary sensory neurons) (12,77,140).”
• The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept (2007, background): “It should be noted, however, that TRPV1 is expressed in higher brain structure”