Proteomic analysis of post-translational modifications
By Matthias Mann, Ole Nørregaard Jensen. Nature Biotechnology, 2003
2,039 citations recorded by the source corpus.
Subfields: Oncology, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/a67f329365ffdaf713215e640ed7081b9b8afe81
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Oncology
In Spectroscopy
- Matthias Mann
- Jesper V. Olsen
- John R. Yates III
- Shao-En Ong
- C. Ruse
- A. Nakorchevsky
- P. Mortensen
- S. Mohammed
Citations in the corpus
- The role of dehydrins in plant response to cold (2007, background): “In addition, many proteins are modified by posttranslational modifications such as phosphorylation, glucosylation, ubiquitinylation, sumoylation, and many others (Mann and Jensen, 2003; Schweppe et al., 2003; Canovas et al., 2004) which significantly influence protein functions.”
- Post-translational modifications in proteins: resources, tools and prediction methods (2021, background): “PTMs play a key role innumerous biological processes by significantly affecting the structure and dynamics of proteins (2, 3).”
- The Kinome of Pacific Oyster Crassostrea gigas, Its Expression during Development and in Response to Environmental Factors (2016, positive): “PTMs change protein properties either by proteolytic cleavage or by addition of a modifying group to one or several amino acids [7].”
- Quantitative Phosphoproteomics Applied to the Yeast Pheromone Signaling Pathway*S (2005, background): “A major challenge in proteomics is to define the characteristics and dynamics of post-translational modifications in cells, tissues, and organisms ( 1 , 2). Protein phosphorylation, one of the most important and best characterized post-translational modifications, plays a key role in eukaryotic sign”
- A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC) (2006, background): “Analysis of PTMs is one of the unique strengths of proteomic”
- From genomics to proteomics (2003, background): “As refinements are made in next-generation proteomic instruments, it will be possible to monitor many relevant post-translational modifications and protein interactions in ever more complex mixture”