Dynamics of microglial activation: A confocal time‐lapse analysis in hippocampal slices

By N. Stence, Marc Waite, M. Dailey. Glia, 2001

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The P2Y12 receptor regulates microglial activation by extracellular nucleotides (2006, neutral): “dtd" [ ]> In the spinal cord and brain, microglia migrate or project cellular processes toward sites of mechanical injury or tissue damag”
Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration (2003, background): “Initially, quiescent microglial cells retract their ramifications , transforming themselves into amoeboid-like cells with motile protrusions (Stence et al., 2001).”
Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness (2016, background): “When a challenge is present, these cells become amoeboid-like, with enlarged soma, fewer branches and processes (Davalos et al. 2005; Stence et al. 2001).”
Overview of General and Discriminating Markers of Differential Microglia Phenotypes (2020, background): “Although adult microglial cells are considered rather functionally homogenous, they show a broad spectrum of intrinsic heterogeneity (Stratoulias et al., 2019; Tan et al., 2020).”
Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke. (2016, background): “Once brain injury occurs, the microglia change their morphology, which includes the development of motile branches or the migration of the somata (Nolte et al., 1996; Stence et al., 2001), and become activated to damage or repair brain tissue.”