Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens

By Esther M. Sternberg. Nature reviews. Immunology, 2006

1,050 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/a61acc44b3cd82309d92bd4f734d71fb40b0ce21

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Citations in the corpus

Neuroinflammation and depression: A review (2020, background): “Peripheral, circulating inflammatory mediators also affect HPA axis activity, reaching the hypothalamus directly through the endothelium of the circumventricular organs or an altered BBB (Bellavance & Rivest, 2014) or indirectly through afferent fibres from the vagus nerve conveying information abou”
The Bidirectional Relationship of Depression and Inflammation: Double Trouble (2020, background): “The HPA axis and the sympathetic nervous system (SNS) are activated in response to various types of stress and are known to be immunoregulatory (for review, see Sternberg, 2006).”
Early-Life Adversity and Physical and Emotional Health across the Lifespan: A Neuro-Immune Network Hypothesis (2015, background): “These hormones initially reinforce norepinephrine’s proinflammatory actions, but as the threat subsides, they counter-regulate it (61,64).”
From Stress to Inflammation and Major Depressive Disorder: A Social Signal Transduction Theory of Depression (2014, background): “…stressors, as well as in modulating immune system reactivity to physical and social threat (McEwen & Gianaros, 2010; Pavlov & Tracey, 2004; Sternberg, 2006), it might be expected that individual differences exist in the extent to which people mount an inflammatory response to social…”
Norepinephrine and octopamine: linking stress and immune function across phyla (2008, background): “The complexity of the effects of NE on vertebrate immune function has prevented a clear adaptive explanation for these changes (Sternberg, 2006).”
Temperature extremes and butterfly fitness: conflicting evidence from life history and immune function (2011, background): “Note in this context that in mammals two mediators of the response to acute stress, norepinephrine and glucocorticoids, are known to be immunosuppressive thus decreasing disease resistance (e.g. Webster et al., 2002; Cao et al., 2003; Sternberg, 2006; Emeny et al., 2007).”
Macrophages, Foreign Body Giant Cells and Their Response to Implantable Biomaterials (2015, background): “immune response, leads to the release of corticosteroids, which can work to inhibit pro-inflammatory cytokines [45].”
Exploring the full spectrum of macrophage activation (2008, background): “glucocorticoids are released by adrenal cells in response to stress and can inhibit macrophage-mediated host defence and inflammatory functions by inhibiting the transcription of pro-inflammatory cytokine genes and decreasing mRNA stabilit”
Harmful molecular mechanisms in sepsis (2008, background): “The main pathways involved in this crosstalk are the hypothalamic–pituitary–adrenal axis and the AN”
ELEVATED INFLAMMATION LEVELS IN DEPRESSED ADULTS WITH A HISTORY OF CHILDHOOD MALTREATMENT (2008, neutral): “On the one hand, brain functioning regulates secretion of glucocorticoid hormones, and glucocorticoids can inhibit inflammation processes.(8) On the other hand, inflammation reduces glucocorticoid signaling, and reduced glucocorticoid signaling may lead to abnormal brain functioning.”
Psychological Stress in Childhood and Susceptibility to the Chronic Diseases of Aging: Moving Towards a Model of Behavioral and Biological Mechanisms (2011, background): “Some authors have argued that stress contributes to disease by creating “imbalances” amongst systems, rather than affecting any singular biological process (McEwen & Stellar, 1993; Thayer & Sternberg, 2006).”
Factors affecting wound healing (2010, background): “Furthermore, GCs influence immune cells by suppressing differentiation and proliferation, regulating gene transcription, and reducing expression of cell adhesion molecules that are involved in immune cell trafficking (Sternberg, 2006).”
Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients (2012, neutral): “In combination, the molecules released during the stress response have profound effects on the function of most cells and organs throughout the body including the brain, heart, respiratory system, muscles, skin, liver, gastrointestinal tract, and, importantly, the immune system.(21) Activation of th”