iProX: an integrated proteome resource
By Jie Ma, Tao Chen, Songfeng Wu, Chunyuan Yang, Mingze Bai, Kun-xian Shu, Kenli Li, Guoqing Zhang, Zhong Jin, F. He and 2 more. Nucleic Acids Res., 2018
1,618 citations recorded by the source corpus.
Abstract Sharing of research data in public repositories has become best practice in academia. With the accumulation of massive data, network bandwidth and storage requirements are rapidly increasing. The ProteomeXchange (PX) consortium implements a mode of centralized metadata and distributed raw data management, which promotes effective data sharing. To facilitate open access of proteome data worldwide, we have developed the integrated proteome resource iProX (http://www.iprox.org) as a public platform for collecting and sharing raw data, analysis results and metadata obtained from proteomics experiments. The iProX repository employs a web-based proteome data submission process and open sharing of mass spectrometry-based proteomics datasets. Also, it deploys extensive controlled vocabularies and ontologies to annotate proteomics datasets. Users can use a GUI to provide and access data through a fast Aspera-based transfer tool. iProX is a full member of the PX consortium; all released datasets are freely accessible to the public. iProX is based on a high availability architecture and has been deployed as part of the proteomics infrastructure of China, ensuring long-term and stable resource support. iProX will facilitate worldwide data analysis and sharing of proteomics experiments.
Subfields: Molecular Biology, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/a5c68025524d20e14e9ca263a380978b2cfbf92c
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In Molecular Biology
- Zhi Sun
- Brendan MacLean
- Alvis Brazma
- Eric W. Deutsch
- Michael J. MacCoss
- Juan Antonio Vizcaíno
- Yasushi Ishihama
- Alexey I. Nesvizhskii
In Spectroscopy
- Zhi Sun
- Brendan MacLean
- Eric W. Deutsch
- Michael J. MacCoss
- Juan Antonio Vizcaíno
- Yasushi Ishihama
- Matthias Mann
- Alexey I. Nesvizhskii
Citations in the corpus
- The ProteomeXchange consortium in 2020: enabling ‘big data’ approaches in proteomics (2019, background): “Two additional resources have joined the consortium in the last three years: iProX (12) (National Center for Protein Sciences, Beijing, China) in 2017, and Panorama Public (13) (University of Washington, Seattle, WA, USA) in 2018.”
- The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences (2021, background): “As of 2021, the resources PeptideAtlas (13), including its related resource PASSEL (PeptideAtlas SRM Experiment Library) (14), MassIVE (15), jPOST (16), iProX (17) and Panorama Public (18) are the active members of the consortium.”