The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

By S. McAllister, R. Weinberg. Nature Cell Biology, 2014

860 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/a5602295100eebb0898e870c58bc330da5a09414

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In Cancer Research

In Oncology

Citations in the corpus

Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications (2019, background): “most of the current paradigms are designed to eliminate or interdict tumor cells themselves while the successful outgrowth of metastases is largely influenced by nonmalignant cells of the tumor microenvironment (TME) [5, 6, 82].”
Characteristics and Significance of the Pre-metastatic Niche. (2016, background): “Some regulatory or immunosuppressive cells, such as MDSCs, macrophages, and Treg cells within the pre-metastatic niche potentially suppress anti-tumor immune responses (Liu and Cao, 2016; McAllister and Weinberg, 2014).”
ESPEN expert group recommendations for action against cancer-related malnutrition. (2017, neutral): “, interleukin 1 (IL-1), IL-6, and tumor necrosis factor-a (TNF-a) [37,38].”
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics (2015, neutral): “It has been reported that tumor-educated platelets (TEPs) may enable blood-based cancer diagnostics (Calverley et al., 2010; McAllister and Weinberg, 2014; Nilsson et al., 2011).”
EMERGING BIOLOGICAL PRINCIPLES OF METASTASIS (2017, positive): “…a primary tumor can lead to the production of numerous systemic signaling factors that, by acting on distant tissues, can elicit responses that may thereafter affect primary tumor growth, pre-metastatic niches, and the outgrowth of previously latent micrometastases (McAllister and Weinberg, 2014).”