Aging of the brain and its impact on cognitive performance: Integration of structural and functional findings.

By Naftali Raz. 2000

1,200 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/a5372d3613526fc8716cc25b87d1ff7137ac5743

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Citations in the corpus

Source monitoring 15 years later: What have we learned from fMRI about the neural mechanisms of source memory? (2009, methodology): “Consistent with this pattern, age-associated neuropathology in medial temporal regions has been found (Golomb et al., 1996; O’Brien, Desmond, Ames, Schweitzer, & Tress, 1997; Raz, 2000; Raz et al., 2005; Small, Tsai, De La Paz, Mayeux, & Stern, 2002).”
Thinning of the cerebral cortex in aging. (2004, methodology): “Thus, the data suggest a heterochronous nature of morphological alterations that is anatomically widespread and agrees with the suggestion that ‘the aging brain exhibits a patchwork pattern of differential declines and relative preservation’ (Raz, 2000).”
Differential effects of age on item and associative measures of memory: a meta-analysis. (2008, background): “, & Raz, N. (1994). Memory for facts, source, and context: Can frontal lobe dysfunction explain age-related differences? Psychology and Aging, 9, 149–159. Spencer, W. D., & Raz, N. (1995). Differential effects of aging on memory for content and context: A meta-analysis. Psychology and Aging, 10, 527”
Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis. (2004, background): “Grey matter in many neocortical areas shows age-related volume reductions that are at least as large as those observed in the hippocampus (Coffey, 2000; Raz, 2000).”
Hemispheric asymmetry reduction in older adults: the HAROLD model. (2002, background): “PFC is the brain region that is most affected by age-related neural changes (for reviews, see Cabeza, 2001; Raz, 2000) and, according to a popular view, is the locus of age-related deficits in cognition (West, 1996).”
Moving toward a neuroplasticity view of bilingualism, executive control, and aging (2014, background): “Advanced aging is generally associated with reductions in gray and white matter density (atrophy; e.g., Kennedy & Raz, 2009), with the frontal lobes most susceptible to deterioration (McGinnis, Brickhouse, Pascual, & Dickerson, 2011; Raz, 2000; Raz et al., 2005; West, 1996).”
Age Differences in the Frontal Lateralization of Verbal and Spatial Working Memory Revealed by PET (2000, background): “Prefrontal regions seem particularly vulnerable to the effects of aging (Raz, in press) and changes in frontal lobe function are hypothesized to be the source of various cognitive deficits found in older adults (see Moscovitch & Winocur, 1995; Raz, in press for reviews).”
Frontal circuitry degradation marks healthy adult aging: Evidence from diffusion tensor imaging (2005, background): “Although a large body of studies (for reviews, Buckner, 2004; Hedden and Gabrieli, 2004; Raz, 1999; but see Greenwood, 2000) supports the position that as a group older, healthy individuals are likely to exhibit poorer executive functioning than younger individuals, we do not have…”
Language and Aging (2007, unknown): “…Zonderman, & Davatzikos, 2003; Sowell, Peterson, Thompson, Welcome, Henkenius, & Toga, 2003) and fMRI has demonstrated that age differences are found in neural activation of some brain regions and not others (see Raz, 2000 for an excellent review of differential vulnerability of neural regions).”
Disruption of large-scale brain systems in advanced aging. (2007, background): “Furthermore, information concerning which brain systems are functionally disrupted in aging is lacking, although the consensus derived from structural analyses is that anterior brain regions show preferential gray matter volume loss and reduced white matter integrity (Sullivan and Pfefferbaum, 2006;”
Growing together and growing apart: Regional and sex differences in the lifespan developmental trajectories of functional homotopy (2010, methodology): “This ordering is consistent with a “last-in-firstout” aging effect, which has been described previously for measures of white matter integrity (Raz, 2000; Davis et al., 2009).”
Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans. (2005, background): “While the control subjects showed a non-significant negative correlation (r = 0.165) between hippocampal volume and age, which was within the range of values in normal ageing (Raz, 2000), BVL patients had a positive, non-significant correlation between age and hippocampal volume (r = 0.12).”
Aging Gracefully: Compensatory Brain Activity in High-Performing Older Adults (2002, background): “As we age, our brain undergoes a series of deleterious changes, including grey and white matter atrophy, synaptic degeneration, blood flow reductions, and neurochemical alterations (Raz, 2000; Cabeza, 2001).”