Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage.

By P. Kannouche, J. Wing, A. Lehmann. Molecules and Cells, 2004

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Citations in the corpus

A novel function of DNA polymerase ζ regulated by PCNA (2006, background): “…modification of proliferating cell nuclear antigen (PCNA), an accessory factor of replicative DNA polymerases, is important for the switch from the replicative polymerase to a TLS polymerase (Hoege et al, 2002; Stelter and Ulrich, 2003; Haracska et al, 2004; Kannouche et al, 2004).”
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? (2004, background): “Lys 164 in yeast PCNA is the major site of modification by both SUMO and ubiquitin; ubiquitination at this position is conserved in human PCNA although SUMO modification of human PCNA has not been described (Hoege et al. 2002; Kannouche et al. 2004).”
Regulation of the Rev1–pol ζ complex during bypass of a DNA interstrand cross‐link (2015, neutral): “In response to replication fork stalling, PCNA is mono-ubiquitylated by Rad6/ Rad18 on lysine 164 (Kannouche et al , 2004; Watanabe et al , 2004).”
PCNA, the maestro of the replication fork. (2007, neutral): “Yeast genetic studies indicated that monoubiquitylated PCNA is linked to the TLS polymerases Polη (Rad30) and Polζ (Rev3/Rev7) (Stelter and Ulrich, 2003), and indeed human Polη was found to interact specifically with monoubiquitylated PCNA (Kannouche et al., 2004; Watanabe et al., 2004) (Figure 3B).”
Loss of DNA Polymerase ζ Causes Chromosomal Instability in Mammalian Cells (2006, background): “i(13) rob(4;14) der(1)t(1;5) dic(17) der(19)ins(3;19) i(13)t(13;14)”