Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.

By A. Kissebah, G. Sonnenberg, Joel Myklebust, Michael D. Goldstein, Karl W. Broman, R. James, Jacqueline Marks, G. Krakower, H. Jacob, J. Weber and 3 more. Proceedings of the National Academy of Sciences of the United States of America, 2000

674 citations recorded by the source corpus.

Subfields: Genetics

View Paper: https://www.semanticscholar.org/paper/a3babd9798f722b429acdb51de5c67b6ec3beeb8

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In Genetics

1. M. Matsuda
2. I. Shimomura

Citations in the corpus

• The Human Obesity Gene Map: The 2005 Update (2006, neutral): “7 (1229) 2209 subjects, 507 families Leptin LOD 5 (1248) 1055 pairs BMI LOD 2.”
• Adiponectin: action, regulation and association to insulin sensitivity (2005, background): “other candidate genes with phenotypes related to features of the metabolic syndrome (14).”
• Metabolic Syndrome: Updates on Pathophysiology and Management in 2021 (2022, background): “The human fetuin-A or the AHSG gene is located on chromosome 3q27, which has been identified as T2DM susceptibility locus [95] and has been mapped as a quantitative trait locus for MetS [96].”
• Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial Dysfunction (2017, background): “This human chromosome 3q27 has been identified as a region carrying a susceptibility gene for type 2 diabetes and metabolic syndrome [20,21].”
• Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies (2015, neutral): “Caucasian individuals from 507 families (27).”
• Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. (2002, background): “, unpublished data) and the metabolic syndrome (12).”