Retroviral Restriction Factor TRIM5α Is a Trimer
By Claudia C. Mische, H. Javanbakht, B. Song, F. Diaz-Griffero, M. Stremlau, B. Strack, Z. Si, J. Sodroski. Journal of Virology, 2005
123 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Immunology, Virology
View Paper: https://www.semanticscholar.org/paper/a3a5f5f6f025955099dbe591c999dfe2f55aa9f2
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In Immunology
Citations in the corpus
- Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by RIG-I (2009, background): “For example, TRIM5a, an intracellular inhibitor of retroviral replication with a structure similar to TRIM25, has been shown to form a trimer in vivo (Mische et al., 2005).”
- TRIM family proteins and their emerging roles in innate immunity (2008, background): “In addition, it has been established that the coiled-coil domain of TRIM5α is required for trimerization and has an important role in the restriction of viral infectivity by this TRIM protei”