Metformin versus insulin for the treatment of gestational diabetes.

By J. Rowan, C. B, W. Hague, Wanzhen Gao, M. Battin, M. Moore. New England Journal of Medicine, 2008

1,066 citations recorded by the source corpus.

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Clinical Pharmacokinetics of Metformin (2011, background): “Metformin is increasingly being used to treat gestational diabetes.([50-52]) Metformin is carried across the placenta by transporters([53]) and the concentrations in the fetus are only slightly lower than in the mother.”
Cellular and molecular mechanisms of metformin: an overview. (2012, result): “Recently, data accumulated from case control studies [144] or the Metformin in Gestational Diabetes Trial [145] suggested that women treated with metformin had less weight gain and improved neonatal outcomes compared with those treated with insulin.”
Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline (2013, positive): “useful to treat gestational diabetes (273).”