Highly expressed genes in yeast evolve slowly.

By Csaba Pál, Balázs Papp, Laurence D. Hurst. Genetics, 2001

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Evolutionary and Physiological Importance of Hub Proteins (2006, unknown): “The HTP-PI network may exhibit a negative correlation between connectivity and evolutionary rate because HTP methods preferentially detect interactions of abundant proteins [15,19] that evolve slower than lowly expressed genes [17].”
Noise Minimization in Eukaryotic Gene Expression (2004, background): “…as it is precisely the opposite of what one would expect if the relationship between the rates of mRNA decay and protein evolution were mediated by the level of expression: slow decay would result in increased expression, which is known to be associated with slow evolution (Pal et al. 2001).”
A Universal Trend of Reduced mRNA Stability near the Translation-Initiation Site in Prokaryotes and Eukaryotes (2010, unknown): “[8,11,13,54–58].”
Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution (2008, unknown): “…mRNA expression levels encode slow-evolving proteins, from bacteria (Drummond et al., 2006; Rocha and Danchin, 2004), yeast (Drummond et al., 2005; Pá l et al., 2001), and algae (Popescu et al., 2006) to nematodes (Krylov et al., 2003), plants (Ingvarsson , 2007; Wright et al., 2004), fruit flies…”