Dual specificity phosphatases: a gene family for control of MAP kinase function

By M. Camps, A. Nichols, S. Arkinstall. The FASEB Journal, 2000

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View Paper: https://www.semanticscholar.org/paper/a305ea5929f27bf02891ff8884ce0c6ae0d757a2

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Citations in the corpus

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases (2007, background): “The dual-specificity MKPs comprise a subfamily of 10 catalytically active proteins, all of which share a common structure comprising an N-terminal noncatalytic domain and a C-terminal catalytic domain (Camps et al., 2000; Theodosiou and Ashworth, 2002).”
Oxidative stress, inflammation, and cancer: how are they linked? (2010, background): “In addition, functional analyses employing knockdown of MKP3, a member of the subfamily of protein tyrosine phosphatases known as dual-specificity phosphatases (MKPs) [269,270], and ectopic overexpression revealed the role of MKP3 in negatively regulating ERK1/2 activity and inhibiting tumorigenicit”
GADD45β/GADD45γ and MEKK4 comprise a genetic pathway mediating STAT4‐independent IFNγ production in T cells (2004, methodology): “We have analyzed the mRNA levels by RT-PCR of three prominent p38 phosphatases, MKP1 (DUSP1), MKP5 (DUSP10), and M3/6 (DUSP8) (Camps et al, 2000; Theodosiou and Ashworth, 2002), in the MEKK4þ /þ and / T cells.”
Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α (2001, background): “…inhibited by dual-specificity phosphatases that are transcriptionally induced by mitogen-activated protein kinase signaling (English et al., 1999; Camps et al., 2000), and cytokine signaling is inhibited by products of suppressor of cytokine signaling (SOCS) genes that are themselves positively…”