A new evolutionary scenario for the Mycobacterium tuberculosis complex

By R. Brosch, S. Gordon, M. Marmiesse, P. Brodin, C. Buchrieser, K. Eiglmeier, T. Garnier, C. Gutiérrez, G. Hewinson, K. Kremer and 5 more. Proceedings of the National Academy of Sciences of the United States of America, 2002

1,565 citations recorded by the source corpus.

Subfields: Epidemiology, Infectious Diseases, Surgery

View Paper: https://www.semanticscholar.org/paper/a209d66919b3d3cc0a6494ac652e53585a7539ef

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Stefan Niemann
2. I. Smith
3. D. Russell

In Infectious Diseases

1. Stefan Niemann
2. I. Smith
3. D. Russell
4. Michal Feldman

In Surgery

1. Kenneth A. Jacobson
2. I. Smith

Citations in the corpus

• Ancient Origin and Gene Mosaicism of the Progenitor of Mycobacterium tuberculosis (2005, methodology): “(F) Southern blot analysis with a DNA probe directed against region RD12can.”
• Who puts the tubercle in tuberculosis? (2007, background): “bovis , or the two strains evolved in parallel from a founder strain that infected both humans and cattl”
• Hematoxylin and eosin staining of tissue and cell sections. (2008, background): “O gênero Mycobacterium inclui o complexo Mycobacterium tuberculosis; o complexo Mycobacterium avium; outras micobactérias e numerosas espécies saprófitas presentes no solo e na água(BROSCH et al., 2002).”
• Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation. (2003, neutral): “Of these, only 1 region of difference, RD1, is missing from every BCG strain analyzed to date but is present in every MTB [10, 11].”
• Bracken: estimating species abundance in metagenomics data (2016, neutral): “As a compromise, taxonomists have created the category Mycobacterium tuberculosis complex (Brosch et al., 2002) to represent a collection of taxa that now includes more than 100 strains of five different species.”
• Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence (2003, background): “tuberculosis complex (38), but the existence of rare synonymous single-nucleotide polymorphisms (sSNP) allows discrimination between these closely related bacteria.”
• High Functional Diversity in Mycobacterium tuberculosis Driven by Genetic Drift and Human Demography (2008, positive): “The primary branches of our sequence-based tree are also consistent with earlier studies that classified M. tuberculosis into ‘‘ancient’’ and ‘‘modern’’ forms based on the presence or absence of a genomic deletion known as TbD1 [8].”
• M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. (2007, background): “*Correspondence: p.peters@nki.nl DOI 10.1016/j.cell.2007.05.059”
• MIRU-VNTRplus: a web tool for polyphasic genotyping of Mycobacterium tuberculosis complex bacteria (2010, background): “Furthermore, the following typing data are supported: presence or absence of 43 spoligotyping spacers, presence or absence of 15 standard LSPs (6,7), values of six SNPs (20) and susceptibility data for 16 drugs.”