Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation.

By Kaeryn N Lewis, R. Liao, Kristine M. Guinn, M. Hickey, Sherilyn Smith, Marcel Behr, David R. Sherman. Journal of Infectious Diseases, 2003

621 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/ef90d3df34b453a460a6a9806a4e8ff895fa4e2d

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Citations in the corpus

• Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence (2003, background): “bovis BCG strains have one common deletion, RD1, that causes their attenuated phenotype (162, 227).”
• M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. (2007, background): “The ESX-1 region has an important role in the virulence of M. tuberculosis (Lewis et al., 2003; Hsu et al., 2003; Stanley et al., 2003).”