Nuclear hormone receptors and gene expression.

By A. Aranda, Á. Pascual. Physiological Reviews, 2001

1,578 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a02d7895847f90a284610699655f056600b4b8e1

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Citations in the corpus

DNA Methylation of Estrogen Receptor α Gene by Phthalates (2005, background): “Most of the cellular actions of steroid hormones are mediated by their binding to nuclear receptors (NRs), which act as ligand-inducible transcription factors ( Aranda & Pascual 2001 ).”
Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. (2005, background): “Nuclear receptors regulate transcription, in part, by binding specific DNA sequences known collectively as hormone response elements, which are generally composed of tandem hexameric motifs and normally located in the 5 -flanking region of target genes (15).”
Binding of brassinosteroids to the extracellular domain of plant receptor kinase BRI1 (2005, background): “Animal steroids are principally recognized by members of the nuclear receptor superfamily of transcription factor”
Estrogen signaling multiple pathways to impact gene transcription. (2006, background): “ER activates transcription in the presence of E2, whereas ER -E2 inhibits AP-1-dependent transcription [74, 60].”
Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain. (2002, background): “Steroid hormones regulate cellular events most commonly by acting as ligand-activated transcription factors (Aranda & Pascual 2001, Zhang & Lazar 2000), so the possible hormonal regulation of antiapoptotic to proapoptotic proteins represents a likely mechanism for influencing cell death.”
Nuclear retinoid receptors and the transcription of retinoid-target genes. (2004, background): “The phosphorylation of corepressors such as SMRT correlates with an inhibition of their interaction with RARs and their redistribution from the nucleus to the cytoplasm (Hong and Privalsky, 2000).”
A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health. (2018, background): “Some RXR heterodimers respond to ligands of either partner and are synergistically activated when both ligands are bound, providing a mechanism for widespread effects of retinoids on gene expression [437].”
Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism (2009, background): “…hormone receptors in the 1980s led to an intense search by many laboratories for additional, novel members of the steroid hormone superfamily [Aranda and Pascual, 2001; Desvergne and Wahli, 1999; Escriva et al., 2000; Evans, 1988; Giguere, 1999; Kumar and Thompson, 1999; Novac and Heinzel,…”