Effect of polymorphisms on ligand binding by mouse major urinary proteins
By Amr Darwish Marie, C. Veggerby, D. Robertson, S. Gaskell, S. Hubbard, L. Martinsen, Jane Hurst, R. Beynon. 2001
63 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Immunology and Allergy, Sensory Systems
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cellular and Molecular Neuroscience
In Sensory Systems
Citations in the corpus
- Pheromone binding by polymorphic mouse major urinary proteins (2002, background): “However, there are apparently many additional MUPs that could be tested, and Marie et al. (2000) have noted that the role of MUPs in ligand release indicates that the polymorphisms may lead to different binding characteristics for molecules that occupy the central calyx.”
- Individual recognition in mice mediated by major urinary proteins (2001, background): “Although most polymorphism occurs on the surface of the protein, some variants occur in the cavity-binding site and we have shown that these variants are able to modulate binding of ligand”
- The binding cavity of mouse major urinary protein is optimised for a variety of ligand binding modes. (2009, methodology): “Starting from the model of NPN bound to MUP reported in [8] these distance restraints were used in an energy minimisation, with X-PLOR [10], to optimise the position of NPN in the protein cavity.”
- Individual recognition by scent (2004, background): “This cavity is flexible and is able to accommodate a wide range of small molecules including environmentally derived chemicals (Robertson et al. 1998), reporter molecules (Marie et al. 2001) and a variety of specific pheromones (Novonty et al. 1999, Sharrow et al. 2002).”
- The Structure, Stability and Pheromone Binding of the Male Mouse Protein Sex Pheromone Darcin (2014, background): “The larger NPN bound MUP11 (and other MUPs [27]) but not darcin.”
- Polymorphism in Major Urinary Proteins: Molecular Heterogeneity in a Wild Mouse Population (2002, background): “Although there is some variation in ligand binding capability between different MUPs (Marie et al., 2001; Robertson et al., 2001), differential ligand release kinetics seems inadequate as an explanation for MUP diversity, since many MUPs show similar ligand binding properties.”